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Choosing the Right Product

A variety of quality of life issues can also be improved through physical activity.  These include range of motion, pain reduction, and emotional well-being.

 

 

This diagram illustrates one of the ways physical activity helps to lower blood glucose levels.  Increasing the number and activity of insulin receptors (marked in red) on the surface of muscle cells accelerates the uptake of glucose.  A special enzyme called “glut 4,” (the orange opening) produced during exercise, enhances glucose uptake in a non-insulin-dependent manner.  These physiologic changes help the body to become much more efficient at metabolizing glucose for energy.

 

Who is At Risk for Hypoglycemia?

Fear of hypoglycemia is one of the major obstacles to exercise for people with diabetes and their healthcare providers.  However, it is important to remember that hypoglycemia will not occur unless a patient is taking insulin or oral hypoglycemic agents – sulfonylureas or meglitinides.  No other diabetes medications or treatments produce hypoglycemia.

 

 

 

Those who use premixed insulin (a combination of NPH and regular or rapid insulin) are at the greatest risk for hypoglycemia during exercise due to the untimely and inconsistent peak of the daytime NPH insulin.  Those taking oral medications that stimulate the production of extra insulin by the pancreas are at a small but ever-present risk of hypoglycemia. 

 

Attention must be given to making intelligent adjustments to minimize hypoglycemia risk in these individuals.

 

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