The “Balancing
Act” of Blood Glucose Management
Other factors
besides food and carbohydrates can increase the level of glucose in the blood.
Illness and stress cause hormones and other chemicals to be produced which cause
temporary insulin resistance and elevated blood sugars. Many counterregulatory
hormones stimulate the liver to secrete extra glucose into the bloodstream.
On the other
side of the scale are the agents that make blood sugar go down: physical
activity, insulin, and oral diabetes medications. The key to successful blood
sugar management is finding a balance between all these factors and maintaining
blood sugars as close to the normal range as possible – without going too high
or too low.
Hormonal Influences on Glucose Secretion
Many hormones,
include glucagon, adrenaline (epinephrine), noradrenaline (norepinephrine),
cortisol, growth hormones and sex hormones stimulate the liver to produce
glucose. This, in turn, creates the need for ongoing “basal” insulin. In most
people, the liver secretes glucose in a diurnal manner, with greater secretion
at certain hours of the day, and less secretion at others. |
|
Offsetting Hepatic Glucose Output: Basal Insulin
•Offsets
Hepatic Glucose Output
•Regulates
Fasting Glucose
•Supplies
Fuel for Basic Metabolism
•Usually
approx. 50% of Total Daily Insulin
•Levels
Vary by Time of Day
Thus, basal
insulin’s job is to offset hepatic glucose output. Without basal insulin, the
liver would secrete excessive amounts of glucose, and this glucose would remain
in the bloodstream, causing damage to blood vessels and key organs. The body’s
cells would starve for fuel, and ketosis or ketoacidosis could develop.
Carbohydrate Metabolism
Food sources
that traditionally affect blood sugar levels are carbohydrates such as sugars
and starches. This includes potatoes, bread, rice, crackers and sweets. Proteins
and fats do not generally affect blood sugar unless consumed in large quantities
on in the absence of carbohydrates.
It is important
to note that all carbohydrates, whether they be simple or complex, will
ultimately be converted into glucose that enters the bloodstream.