Sub-classifications
of GDM
There are two
sub-classifications of gestational diabetes mellitus. Class A 1 is able to
maintain glycemic control by following a meal plan and not using any
medications. Class A 2 requires a specialized meal plan as well as insulin or
oral agents in order to maintain glycemic control.
Fetal Monitoring
Fetal monitoring
is done through a series of tests, alone or in various combinations, and
maybegin as early as 28 weeks. Let’s take a minute and go over these tests.
The non-stress
test, or NST, measures the acceleration of the fetal heart rate in response to
fetal activity. A Doppler ultrasound is used. A non-reactive test result is an
indication for more fetal monitoring.
A biophysical
profile is a combination of ultrasound with the NST. It measures fetal heart
rate, breathing, body movement, muscle tone, and amniotic fluid volume.
An ultrasound
measurement of fetal abdominal circumference, along with self-monitoring of
blood glucose provides useful information to help guide management decisions. If
the infant’s abdomen is <75 percentile for gestational age the physician may
consider less intensive management (meaning less SMBG monitoring). If the
abdominal girth is excessive, the physician may choose to intensify treatment by
lowering blood glucose targets or adding medications or insulin.
Additionally, the
ADA recommends that mothers with gestational diabetes should be taught how to
monitor fetal movement during the last 8-10 weeks of pregnancy.
Amniocentesis is
used to monitor for genetic or chromosomal disorders.
And the
Contraction Stress Test measures fetal heart rate in response to uterine
contractions. To induce mild contractions either a low dose of oxycotin is
administered or the mother’s nipples are stimulated. A negative test result is
associated with good fetal outcomes.
Maternal Monitoring: Blood Glucose Testing
BG
is checked 4 times daily fasting &
1 hr or 2 hrs after meals |
TIME |
mg/dl |
Before
breakfast |
<
96 mg/dl |
1 hour
after
meals |
<
140 mg/dl |
2
hours after meals |
<
120 mg/dl |
|
|
Observational
studies suggest that when average glucose levels are maintained at < 87 mg/dL,
there is an increased likelihood of the infant being small for their gestational
age (or SGA).
The presence of
ketones may indicate an inadequate intake of energy or carbohydrates. Research
has suggested that ketones in the blood may decrease an infant’s intelligence.
Ketone
testing is recommended for patients with:
Weight loss during treatment
Concerns about possible “starvation ketosis”
|
|
The usefulness of
HA1c testing in women with gestational diabetes is unclear. It may be useful if
gestational diabetes is diagnosed before 20 weeks gestation.
Because of
the increased risk of hypertension, measurement of blood
pressure
and urinary
protein is
recommended
at each prenatal visit to detect the development of preeclampsia.
Pregnant women
with gestational diabetes are at an increased risk for hypertension, so routine
testing of blood pressure and urinary protein is recommended at each prenatal
visit.
Also the frequency
of spontaneous preterm birth may be increased in women with untreated
gestational diabetes. When indicated, corticosteroids may be used to enhance
fetal lung maturity.